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G Behre Selected Research

CCAAT-Enhancer-Binding Protein-alpha

11/2017C/EBPα deregulation as a paradigm for leukemogenesis.
4/2013E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPα for ubiquitin-mediated proteasome degradation.
5/2010Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML.
12/2006Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.
4/2001AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.
3/2001Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.

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G Behre Research Topics

Disease

8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/2015 - 03/2001
7Leukemia
11/2017 - 04/2001
2Neoplasms (Cancer)
12/2015 - 05/2010
1Graft vs Host Disease (Graft-Versus-Host Disease)
12/2015
1B-Cell Lymphoma (Lymphoma, B Cell)
03/2014
1Splenomegaly
02/2014
1Primary Myelofibrosis (Myelosclerosis)
02/2014
1Rare Diseases (Rare Disease)
10/2010
1Hepatitis
10/2010
1Encephalitis (Encephalitis, Rasmussen)
01/2009
1Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2008
1Stomatitis
08/2008
1Diffuse Scleroderma (Progressive Systemic Sclerosis)
05/2008
1Chromosome Aberrations (Chromosome Abnormalities)
11/2006
1Fever (Fevers)
07/2002
1Sepsis (Septicemia)
07/2002
1Neutropenia
07/2002
1Myeloid Leukemia (Leukemia, Myelocytic)
04/2001

Drug/Important Bio-Agent (IBA)

6CCAAT-Enhancer-Binding Protein-alphaIBA
11/2017 - 03/2001
2Transcription Factors (Transcription Factor)IBA
03/2007 - 12/2006
2Proteins (Proteins, Gene)FDA Link
11/2006 - 04/2001
1Cyclosporine (Ciclosporin)FDA LinkGeneric
12/2015
1MicroRNAs (MicroRNA)IBA
03/2015
1fms-Like Tyrosine Kinase 3IBA
03/2015
1Rituximab (Mabthera)FDA Link
03/2014
1CytokinesIBA
02/2014
1Phosphotransferases (Kinase)IBA
02/2014
1ruxolitinibIBA
02/2014
1Protein Isoforms (Isoforms)IBA
04/2013
1Heme (Haem)IBA
10/2010
1Caspofungin (Cancidas)FDA Link
01/2009
1Fibroblast Growth Factor 7FDA Link
08/2008
1Opioid Analgesics (Opioids)IBA
08/2008
1Messenger RNA (mRNA)IBA
04/2008
1Tretinoin (Retinoic Acid)FDA LinkGeneric
04/2008
1Lysine Acetyltransferase 5IBA
04/2008
1CCAAT-Enhancer-Binding ProteinsIBA
12/2006
1ProteomeIBA
11/2006
1Peptides (Polypeptides)IBA
11/2006
1Type II Tumor Necrosis Factor ReceptorsIBA
07/2002

Therapy/Procedure

4Stem Cell Transplantation
12/2015 - 08/2008
1Cell Transplantation
02/2014
1Radiotherapy
11/2008
1Hematopoietic Stem Cell Transplantation
11/2008
1Total Parenteral Nutrition
08/2008
1Transplantation
05/2008
1Ligation
05/2008
1Lasers (Laser)
11/2006
1Therapeutics
01/2003
1Drug Therapy (Chemotherapy)
07/2002